BPR1K871
BPR1K871 is a preclinical dual inhibitor targeting FLT3 and AURKA kinases with IC50 values of 19 nM and 22 nM, respectively. It is utilized in cancer research for investigating acute myeloid leukemia (AML), demonstrating anti-proliferative effects in cellular assays and reducing tumor burden in xenograft models.
Product Specifications
CAS Number
2443767-35-7
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CN (C) CCCOc1ccc2c (NCCc3cnc (NC (=O) Nc4cccc (Cl) c4) s3) ncnc2c1
Molecular Formula
C25H28ClN7O2S
Molecular Weight
526.05
Storage Conditions
-20°C
Notes
For research use only.
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