BQ-788
BQ-788 sodium salt is a potent and selective endothelin B (ETB) receptor antagonist, exhibiting an IC50 of 1.2 nM in human Girardi heart cells. This compound is a valuable research tool for investigating the ETB receptor's role in cardiovascular physiology, pulmonary hypertension, and cancer, supporting both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
156161-89-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Endothelin B antagonist
Form
Lyophilized
Smiles
O=C (N1[C@H] (CCC[C@H]1C) C) N[C@@H] (CC (C) (C) C) C (N[C@@H] (C (N[C@@H] (C ([O-]) =O) CCCC) =O) CC2=CN (C (OC) =O) C3=CC=CC=C23) =O.[Na+]
Molecular Formula
C34H51N5NaO7
Molecular Weight
664.80
Storage Conditions
-20°C
Notes
For research use only.
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