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BQ-788

BQ-788 sodium salt is a potent and selective endothelin B (ETB) receptor antagonist, exhibiting an IC50 of 1.2 nM in human Girardi heart cells. This compound is a valuable research tool for investigating the ETB receptor's role in cardiovascular physiology, pulmonary hypertension, and cancer, supporting both in vitro and in vivo experimental studies.

Product Specifications

CAS Number

156161-89-6

Field of Research

Pharmacology & Drug Discovery

Purity

>98%

Bioactivity

Endothelin B antagonist

Form

Lyophilized

Smiles

O=C (N1[C@H] (CCC[C@H]1C) C) N[C@@H] (CC (C) (C) C) C (N[C@@H] (C (N[C@@H] (C ([O-]) =O) CCCC) =O) CC2=CN (C (OC) =O) C3=CC=CC=C23) =O.[Na+]

Molecular Formula

C34H51N5NaO7

Molecular Weight

664.80

Storage Conditions

-20°C

Notes

For research use only.

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