BR351
BR351 is a small molecule, brain-penetrant inhibitor of matrix metalloproteinases (MMPs), exhibiting potent activity against MMP2, MMP8, MMP9, and MMP13 with IC50 values in the low nanomolar range. This compound is a valuable research tool for studying MMP roles in neuroinflammation, blood-brain barrier integrity, and neurodegenerative diseases in both cellular and animal models.
Product Specifications
CAS Number
960113-85-3
Field of Research
Protein Biochemistry
Smiles
N ([C@@H] (C (NO) =O) C (C) C) (S (=O) (=O) C1=CC=C (OCCF) C=C1) CC2=CC=CC=C2
Molecular Formula
C20H25FN2O5S
Molecular Weight
424.49
Storage Conditions
-20°C
Notes
For research use only.
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