BSc5371
BSc5371 is a potent, irreversible inhibitor of FLT3, demonstrating low nanomolar affinity for key mutant forms (including D835H, ITD/D835V, ITD/F691L, and ITD) as well as wild-type FLT3. It is a valuable research tool for investigating FLT3-driven pathologies, such as acute myeloid leukemia, in both cellular and animal models.
Product Specifications
CAS Number
2286419-03-0
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (=C\1/C=2C (NC1=O) =CC=C (NS (C=C) (=O) =O) C2) \C3=C (C) C (C (NCCN (CC) CC) =O) =C (C) N3
Molecular Formula
C24H31N5O4S
Molecular Weight
485.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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