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BSH-IN-1

BSH-IN-1 is a potent, covalent inhibitor of gut bacterial bile salt hydrolases (BSHs), demonstrating high potency with IC50 values of 108 nM and 427 nM against B. longum and B. theta BSH, respectively. This tool compound enables research into microbiome function, supporting in vitro and in vivo studies on host metabolism and bile acid signaling.

Product Specifications

CAS Number

2553217-91-5

Product Name Alternative

BSHIN1, BSH-IN-1, BSH IN 1, Bile salt hydrolase (BSH), PotassiumChannel, Potassium Channel

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.89 mM) ; DMSO:40 mg/mL (97.9 mM)

Smiles

[H][C@]1 ([C@@H] (CCC (CF) =O) C) CC[C@]2 ([C@@]3 ([C@@H] (C[C@@]4 (C[C@@H] (CC[C@@]4 ([C@]3 (CC[C@]12C) [H]) C) O) [H]) O) [H]) [H]

Molecular Formula

C25H41FO3

Molecular Weight

408.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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