BSH-IN-1
BSH-IN-1 is a potent, covalent inhibitor of gut bacterial bile salt hydrolases (BSHs), demonstrating high potency with IC50 values of 108 nM and 427 nM against B. longum and B. theta BSH, respectively. This tool compound enables research into microbiome function, supporting in vitro and in vivo studies on host metabolism and bile acid signaling.
Product Specifications
CAS Number
2553217-91-5
Product Name Alternative
BSHIN1, BSH-IN-1, BSH IN 1, Bile salt hydrolase (BSH), PotassiumChannel, Potassium Channel
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.89 mM) ; DMSO:40 mg/mL (97.9 mM)
Smiles
[H][C@]1 ([C@@H] (CCC (CF) =O) C) CC[C@]2 ([C@@]3 ([C@@H] (C[C@@]4 (C[C@@H] (CC[C@@]4 ([C@]3 (CC[C@]12C) [H]) C) O) [H]) O) [H]) [H]
Molecular Formula
C25H41FO3
Molecular Weight
408.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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