Numidargistat
CB-1158 is a potent, orally bioavailable small molecule inhibitor of human arginase 1 and 2 (IC50 = 86 and 296 nM, respectively) . It is a valuable research tool for studying the role of arginase in immuno-oncology, fibrosis, and cardiovascular disease in both cellular assays and animal models.
Product Specifications
CAS Number
2095732-06-0
Field of Research
Immunology & Inflammation
Smiles
C (O) (=O) [C@@]1 (N) [C@@H] (CCCB (O) O) CN (C ([C@H] (C) N) =O) C1
Molecular Formula
C11H22BN3O5
Molecular Weight
287.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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