CB1 inverse agonist 1
MRL-650 is a potent and selective CB1 receptor inverse agonist with an IC50 of 7.5 nM for CB1 versus 4100 nM for CB2. This orally bioavailable compound exhibits anorexigenic effects in vivo and is a valuable tool for studying cannabinoid receptor pharmacology in metabolic and appetite regulation research.
Product Specifications
CAS Number
852315-00-5
Product Name Alternative
CannabinoidReceptor, Cannabinoid Receptor, CB1, CB1 inverse agonist 1, CB2, MRL 650, MRL650, MRL-650
Field of Research
Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Purity
99.12% (May vary between batches)
Solubility
DMSO:45 mg/mL (87.41 mM)
Smiles
N (C (C) =O) C=1C=2C (=NC (=C (C2) C3=CC=C (Cl) C=C3) C4=C (Cl) C=C (Cl) C=C4) N (C) C (=O) C1C (C) =O
Molecular Formula
C25H18Cl3N3O3
Molecular Weight
514.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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