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CB1 inverse agonist 1

MRL-650 is a potent and selective CB1 receptor inverse agonist with an IC50 of 7.5 nM for CB1 versus 4100 nM for CB2. This orally bioavailable compound exhibits anorexigenic effects in vivo and is a valuable tool for studying cannabinoid receptor pharmacology in metabolic and appetite regulation research.

Product Specifications

CAS Number

852315-00-5

Product Name Alternative

CannabinoidReceptor, Cannabinoid Receptor, CB1, CB1 inverse agonist 1, CB2, MRL 650, MRL650, MRL-650

Field of Research

Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Purity

99.12% (May vary between batches)

Solubility

DMSO:45 mg/mL (87.41 mM)

Smiles

N (C (C) =O) C=1C=2C (=NC (=C (C2) C3=CC=C (Cl) C=C3) C4=C (Cl) C=C (Cl) C=C4) N (C) C (=O) C1C (C) =O

Molecular Formula

C25H18Cl3N3O3

Molecular Weight

514.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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