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AS-0141

AS-0141 (Cdc7-IN-6) is a highly potent and selective inhibitor of Cdc7 kinase, demonstrating an IC50 of 4 nM. It exhibits robust anti-tumor activity in cellular assays and has shown efficacy in reducing tumor growth in preclinical in vivo models, supporting its use in cancer research.

Product Specifications

CAS Number

1402057-88-8

Product Name Alternative

Cdc7-IN-6, Cdc7, AS 0141, AS0141, AS-0141, SRA 141, SRA141, SRA-141, PNT 141, PNT141, PNT-141

Field of Research

Cell Biology

Purity

99.97% (May vary between batches)

Solubility

DMSO:76.5 mg/mL (164.36 mM)

Smiles

N (C1=C (C (OCC) =O) C (=O) C (=CC=2C=3C (NC2) =NC=CC3) O1) N4CCN (CC (F) (F) F) CC4

Molecular Formula

C21H22F3N5O4

Molecular Weight

465.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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