AS-0141
AS-0141 (Cdc7-IN-6) is a highly potent and selective inhibitor of Cdc7 kinase, demonstrating an IC50 of 4 nM. It exhibits robust anti-tumor activity in cellular assays and has shown efficacy in reducing tumor growth in preclinical in vivo models, supporting its use in cancer research.
Product Specifications
CAS Number
1402057-88-8
Product Name Alternative
Cdc7-IN-6, Cdc7, AS 0141, AS0141, AS-0141, SRA 141, SRA141, SRA-141, PNT 141, PNT141, PNT-141
Field of Research
Cell Biology
Purity
99.97% (May vary between batches)
Solubility
DMSO:76.5 mg/mL (164.36 mM)
Smiles
N (C1=C (C (OCC) =O) C (=O) C (=CC=2C=3C (NC2) =NC=CC3) O1) N4CCN (CC (F) (F) F) CC4
Molecular Formula
C21H22F3N5O4
Molecular Weight
465.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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