CDK8/19-IN-1
CDK8/19-IN-1 is a potent, selective, and orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM and 0.99 nM, respectively. It is a valuable research tool for studying the Mediator complex in oncology and inflammation, enabling both in vitro biochemical assays and in vivo model studies.
Product Specifications
CAS Number
1818427-07-4
Field of Research
Cell Biology
Smiles
O (C1=C2C (=C (C (N) =O) S1) CCC3=C2SN=C3) C=4C=CC (C (NCCOC) =O) =NC4
Molecular Formula
C19H18N4O4S2
Molecular Weight
430.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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