SEL120-34A
SEL120-34A is a potent, ATP-competitive inhibitor selective for CDK8, demonstrating antitumor activity. It shows high potency against CDK8/CycC and CDK19/CycC with significantly lower activity against CDK9. This compound is a valuable research tool for studying transcriptional regulation in oncology, with utility in both cellular and in vivo cancer models.
Product Specifications
CAS Number
1609522-33-9
Product Name Alternative
CDK9/cycT, CDK8/CycC, CDK19/CycC, SEL12034A, SEL-120-34A, SEL120-34A, SEL120 34A
Field of Research
Cell Biology
Purity
99.70% (May vary between batches)
Solubility
DMSO:4.15 mg/mL (10.02 mM) ; H2O:< 0.65 mg/mL (1.56mM) (insoluble)
Smiles
CC1=C2C=3N (C (=N2) N4CCNCC4) CCCC3C (Br) =C1Br
Molecular Formula
C15H18Br2N4
Molecular Weight
414.14
Storage Conditions
-20°C
Notes
For research use only.
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