CDK9-IN-7
CDK9-IN-7 is a potent and selective oral inhibitor of the CDK9/cyclin T complex with an IC50 of 11 nM, demonstrating significant selectivity over CDK4/6. This compound is a valuable chemical probe for researching transcription regulation in oncology, particularly in studies of cancer cell proliferation and apoptosis, both in vitro and in vivo.
Product Specifications
CAS Number
2369981-71-3
Product Name Alternative
CDK9IN7, CDK-9-IN-7, CDK9-IN-7, CDK9/cyclin T1, CDK9/cyclinT1, CDK9 IN 7, CDK6/cyclinD, CDK4/CyclinD, CDK4/cyclin D
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.83 mM) ; DMSO:10 mg/mL (18.26 mM)
Smiles
C (N (C) C) (=O) C=1N (C=2C (C1) =CN=C (NC3=CC=C (NC (CCCCCCCN=C=S) =O) C=C3) N2) C4CCCC4
Molecular Formula
C29H37N7O2S
Molecular Weight
547.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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