Cenicriviroc Mesylate
Cenicriviroc Mesylate (TBR-652 Mesylate) is an oral dual antagonist of CCR2 and CCR5 receptors with anti-inflammatory and anti-fibrotic properties. It is utilized in research for liver fibrosis, evidenced by its ability to reduce APRI and FIB-4 scores in both in vitro studies and in vivo preclinical models.
Product Specifications
CAS Number
497223-28-6
Product Name Alternative
TBR 652 Mesylate, TBR652 Mesylate, TBR-652 Mesylate, TAK652 Mesylate, TAK-652 Mesylate, TAK 652 Mesylate, R5 HIV-1, R5 HIV-2, CCR2, Cenicriviroc Mesylate, CCR5
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.16 mM) ; DMSO:80 mg/mL (100.88 mM)
Smiles
CS (O) (=O) =O.CCCCOCCOc1ccc (cc1) -c1ccc2N (CC (C) C) CCC\C (=C/c2c1) C (=O) Nc1ccc (cc1) S (=O) Cc1cncn1CCC
Molecular Formula
C42H56N4O7S2
Molecular Weight
793.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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