Cevipabulin
Cevipabulin (TTI-237) is a microtubule-targeting antitumor agent that competitively inhibits vinblastine binding to tubulin with an IC50 of 18-40 nM. This compound has demonstrated cytotoxic activity in vitro against human cancer cell lines and has been evaluated in vivo for its potential in oncology research, particularly in studies investigating mitotic disruption and apoptosis.
Product Specifications
CAS Number
849550-05-6
Product Name Alternative
Cevipabulin, microtubule, Microtubule Associated, microtubule in human tumor cells, MicrotubuleAssociated, TTI 237, TTI237, TTI-237
Field of Research
Signal Transduction
Purity
99.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.15 mM) ; DMSO:9 mg/mL (19.36 mM)
Smiles
[H][C@@] (C) (Nc1c (c (Cl) nc2ncnn12) -c1c (F) cc (OCCCNC) cc1F) C (F) (F) F
Molecular Formula
C18H18ClF5N6O
Molecular Weight
464.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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