CGP52411
CGP52411 is an orally bioavailable, ATP-competitive EGFR inhibitor (IC50: 0.3 μM) with research applications in Alzheimer's disease. It demonstrates neuroprotective effects by blocking toxic calcium influx and potently inhibiting and reversing Aβ42 fibril aggregation in vitro.
Product Specifications
CAS Number
145915-58-8
Product Name Alternative
β Amyloid, βAmyloid, bAmyloid, Amyloid-β, b Amyloid, CGP 52411, CGP52411, CGP-52411, BetaAmyloid, Beta Amyloid, DAPH, EGFR
Field of Research
Cardiovascular Research, Neuroscience, Signal Transduction
Purity
99.56% (May vary between batches)
Solubility
DMSO:90 mg/mL (273.27 mM)
Smiles
O=C1NC (=O) c2cc (Nc3ccccc3) c (Nc3ccccc3) cc12
Molecular Formula
C20H15N3O2
Molecular Weight
329.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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