CH6953755
CH6953755 is a potent and selective oral YES1 kinase inhibitor with an IC50 of 1.8 nM. It suppresses cancer cell proliferation in vitro and demonstrates antitumor efficacy in vivo, making it a valuable research tool for oncology studies targeting YES1-dependent signaling pathways.
Product Specifications
CAS Number
2055918-71-1
Product Name Alternative
CH-6953755, CH6953755, CH 6953755, Yes1, YES1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:100 mg/mL (180.98 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.24 mM)
Smiles
Cc1cc2cc ([nH]c2cc1NS (C) (=O) =O) C (=O) c1cnn (c1N) -c1cnc (Oc2c (F) cccc2F) cc1C
Molecular Formula
C26H22F2N6O4S
Molecular Weight
552.55
Storage Conditions
-20°C
Notes
For research use only.
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