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CHK1-IN-3

CHK1-IN-3 is a potent and selective checkpoint kinase 1 (CHK1) inhibitor with an IC50 of 0.4 nM. This small molecule is a valuable research tool for investigating DNA damage response pathways in vitro and has been utilized in studies exploring chemosensitization in cellular and preclinical cancer models.

Product Specifications

CAS Number

2097252-39-4

Product Name Alternative

Chk1, CHK1 IN 3, CHK1IN3, CHK-1-IN-3, CHK1-IN-3

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

98.78% (May vary between batches)

Solubility

DMSO:55 mg/mL (135.65 mM)

Smiles

N (C) C=1C (=CN=C (NC=2C=C (O[C@@H]3CCCNC3) C (C#N) =NC2) N1) C4=CN (C) N=C4

Molecular Formula

C20H23N9O

Molecular Weight

405.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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