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CHK1-IN-4 hydrochloride

CHK1-IN-4 hydrochloride is a potent and selective checkpoint kinase 1 (Chk1) inhibitor that suppresses Chk1 phosphorylation in tumor cells. This compound demonstrates anti-tumor activity and is a valuable chemical probe for researching DNA damage response pathways in both cellular and animal models of cancer.

Product Specifications

Product Name Alternative

Chk1, CHK1-IN-4 Hydrochloride, CHK1-IN-4 hydrochloride (2120398-41-4 Free base), 2120398-41-4, 2120398-41-4 Free base

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

98.02% (May vary between batches)

Solubility

DMSO:5 mg/mL (10.4 mM)

Smiles

Cl.COc1cc (Br) cc (OCCCN) c1-c1cc (Nc2cnc (cn2) C#N) n[nH]1

Molecular Formula

C18H19BrClN7O2

Molecular Weight

480.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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