CHMFL-EGFR-202
CHMFL-EGFR-202 is a potent, irreversible EGFR kinase inhibitor, effective against both wild-type and drug-resistant T790M mutant forms with IC50 values of 8.3 nM and 5.3 nM, respectively. It is a valuable research tool for in vitro and in vivo studies targeting EGFR-driven cancers, including non-small cell lung cancer.
Product Specifications
CAS Number
2089381-40-6
Product Name Alternative
CHMFL EGFR 202, CHMFL-EGFR 202, CHMFLEGFR202, CHMFL-EGFR202, CHMFL-EGFR-202, BMX, Btk, BLK, ErbB4, ErbB2, EGFR, EGFRT790M, MEK1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.19% (May vary between batches)
Solubility
DMSO:45 mg/mL (91.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.08 mM)
Smiles
NC1=C2C (=NN (C2=NC=N1) [C@H]3CN (C (C=C) =O) CCC3) C4=CC (Cl) =C (OCC5=CC=CC=N5) C=C4
Molecular Formula
C25H24ClN7O2
Molecular Weight
489.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
24 in replacement HEPA filter for 32 in AirClean combination PCR workstation
