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CHMFL-PI3KD-317

CHMFL-PI3KD-317 is a potent, selective, and orally bioavailable PI3Kδ inhibitor (IC50 = 6 nM) . It effectively blocks PI3Kδ-mediated Akt phosphorylation in Raji cells (EC50 = 4.3 nM) and demonstrates antiproliferative activity, making it a valuable tool for oncology and immunology research in both cellular and animal models.

Product Specifications

CAS Number

2244992-76-3

Product Name Alternative

CHMFL PI3KD 317, CHMFL-PI3KD-317, CHMFL-PI3KD 317, CHMFLPI3KD317, CHMFL-PI3KD317, CHMFL-PI-3KD-317, PI4KIIIβ, PI4KIIIα, PI4KIIIA, PI4KIIIB, PI3Kβ, PI3Kγ, PI3Kδ, PI3Kα, PIK3C2B, Vps34

Field of Research

Signal Transduction

Purity

97.80% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.05 mM) ; DMSO:45 mg/mL (91.09 mM)

Smiles

CC (C) [C@H] (N) C (=O) Nc1nc (C) c (s1) -c1cnc (Cl) c (NS (=O) (=O) c2cccc (C) c2) c1

Molecular Formula

C21H24ClN5O3S2

Molecular Weight

494.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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