CHMFL-PI3KD-317
CHMFL-PI3KD-317 is a potent, selective, and orally bioavailable PI3Kδ inhibitor (IC50 = 6 nM) . It effectively blocks PI3Kδ-mediated Akt phosphorylation in Raji cells (EC50 = 4.3 nM) and demonstrates antiproliferative activity, making it a valuable tool for oncology and immunology research in both cellular and animal models.
Product Specifications
CAS Number
2244992-76-3
Product Name Alternative
CHMFL PI3KD 317, CHMFL-PI3KD-317, CHMFL-PI3KD 317, CHMFLPI3KD317, CHMFL-PI3KD317, CHMFL-PI-3KD-317, PI4KIIIβ, PI4KIIIα, PI4KIIIA, PI4KIIIB, PI3Kβ, PI3Kγ, PI3Kδ, PI3Kα, PIK3C2B, Vps34
Field of Research
Signal Transduction
Purity
97.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.05 mM) ; DMSO:45 mg/mL (91.09 mM)
Smiles
CC (C) [C@H] (N) C (=O) Nc1nc (C) c (s1) -c1cnc (Cl) c (NS (=O) (=O) c2cccc (C) c2) c1
Molecular Formula
C21H24ClN5O3S2
Molecular Weight
494.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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