Chromomycin A3
Chromomycin A3 is a Streptomyces-derived antibiotic that binds GC-rich DNA sequences with divalent cations, blocking replication and transcription. It serves as a fluorescent DNA stain in molecular biology and exhibits anticancer activity in research models for various cancers, including lung adenocarcinoma and melanoma.
Product Specifications
CAS Number
7059-24-7
Product Name Alternative
Aburamycin B; CMA3; NSC-58514
Field of Research
Cell Biology
Purity
>98%
Bioactivity
DNA probe (GC-rich) ; Apoptosis inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
O=C1C=2C (C[C@@] ([C@@H] (C ([C@H] ([C@@H] (C) O) O) =O) OC) ([C@@H]1O[C@H]3C[C@@H] (O[C@H]4C[C@@H] (O[C@H]5C[C@] (C) (O) [C@@H] (OC (C) =O) [C@H] (C) O5) [C@H] (O) [C@@H] (C) O4) [C@H] (O) [C@@H] (C) O3) [H]) =CC=6C (C2O) =C (O) C (C) =C (O[C@H]7C[C@@H] (O[C@@H]8C[C@@H] (O) [C@@H] (OC) [C@@H] (C) O8) [C@@H] (OC (C) =O) [C@@H] (C) O7) C6
Molecular Formula
C57H82O26
Molecular Weight
1183.3
Storage Conditions
-20°C
Notes
For research use only.
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