CM-675
CM-675 is a dual-target small molecule inhibitor of PDE5 and class I HDACs, exhibiting IC50 values of 114 nM and 673 nM against PDE5 and HDAC1, respectively. It has shown potential in Alzheimer's disease research, with studies indicating neuroprotective effects and cognitive improvement in preclinical in vivo models.
Product Specifications
CAS Number
1872466-47-1
Product Name Alternative
CM675, CM-675, CM 675, PDE5
Field of Research
Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Purity
99.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.86 mM) ; DMSO:22.5 mg/mL (41.93 mM)
Smiles
CCCc1nn (C) c2c1nc ([nH]c2=O) -c1cc (Cc2ccc (cc2) C (=O) Nc2ccccc2N) ccc1OCC
Molecular Formula
C31H32N6O3
Molecular Weight
536.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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