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CMLD012073

CMLD012073 is a potent and selective small molecule inhibitor of the eukaryotic initiation factor 4A (eIF4A) RNA helicase, disrupting translation initiation. It exhibits potent activity in cellular models like NIH/3T3 cells (IC50: 10 nM) and is a valuable chemical probe for studying protein synthesis, oncogene expression, and cancer biology in vitro.

Product Specifications

CAS Number

2368900-32-5

Field of Research

Cell Biology

Smiles

O[C@@]12[C@@]3 ([C@] ([C@@H] ([C@H]1C (OC) =O) C4=CC=CC=C4) (OC=5C3=C (OC) C=C (OC) C5) C6=CC=C (OC) C=C6) NC (C) =N2

Molecular Formula

C30H30N2O7

Molecular Weight

530.57

Storage Conditions

-20°C

Notes

For research use only.

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