CMLD012612
CMLD012612 is a potent small molecule inhibitor of eukaryotic initiation factor 4A (eIF4A), demonstrating cytotoxic activity with an IC50 of 2 nM in NIH/3T3 cells by disrupting protein synthesis. This compound is a valuable research tool for studying translation initiation mechanisms in cancer biology and cellular stress responses, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2368900-35-8
Field of Research
Cell Biology
Smiles
CON (C) C (=O) [C@@H]1[C@@H] (c2ccccc2) [C@@]2 (Oc3cc (OC) cc (OC) c3[C@@]22NC (C) =N[C@@]12O) c1ccc (OC) cc1
Molecular Formula
C31H33N3O7
Molecular Weight
559.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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