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CSRM617

CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2), binding its HOX domain with a Kd of 7.43 μM. It induces apoptosis via Caspase-3 and PARP cleavage and has demonstrated good tolerability in a prostate cancer mouse model, supporting its use in oncology research.

Product Specifications

CAS Number

787504-88-5

Field of Research

Cell Biology, Metabolism Research

Smiles

C (=NNC (C (CO) N) =O) C1=C (O) C (O) =C (O) C=C1

Molecular Formula

C10H13N3O5

Molecular Weight

255.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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