CSRM617 hydrochloride
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2), binding its HOX domain with a Kd of 7.43 μM. It induces apoptosis via caspase-3 and PARP cleavage and has demonstrated good tolerability in mouse models of prostate cancer, supporting its use in oncology research.
Product Specifications
CAS Number
1353749-74-2
Product Name Alternative
Androgen Receptor, AndrogenReceptor, CSRM617 Hydrochloride, CSRM-617 Hydrochloride, CSRM617 hydrochloride (787504-88-5 Free base), CSRM 617 Hydrochloride
Field of Research
Cell Biology, Metabolism Research
Purity
99.47% (May vary between batches)
Solubility
DMSO:45 mg/mL (154.27 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.86 mM)
Smiles
Cl.NC (CO) C (=O) N\N=C\c1ccc (O) c (O) c1O
Molecular Formula
C10H14ClN3O5
Molecular Weight
291.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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