Cyclophilin inhibitor 1
Cyclophilin inhibitor 1 is a potent, orally bioavailable small molecule that binds cyclophilin A with high affinity (Kd = 5 nM) . It demonstrates significant antiviral activity against HCV, with an EC50 of 98 nM against the 2a genotype, making it a valuable tool for studying cyclophilin-dependent viral replication in vitro.
Product Specifications
CAS Number
1509904-96-4
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
O=C1C2 (/C=C/C=3C=C4C (=CC3) C=CC (=N4) [C@@H] (C) NC (=O) [C@]5 (NN (C (=O) [C@H] (C) NC (=O) [C@H] (C (C) C) O1) CCC5) [H]) COCOC2
Molecular Formula
C31H39N5O7
Molecular Weight
593.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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