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CYP11B2-IN-1

CYP11B2-IN-1 is a potent and selective small molecule inhibitor, demonstrating high selectivity for aldosterone synthase (CYP11B2, IC50 = 2.3 nM) over cortisol synthase (CYP11B1, IC50 = 142 nM) . It is a valuable research tool for investigating aldosterone-related pathophysiology in both cellular and animal models of hypertension and heart failure.

Product Specifications

CAS Number

1356479-78-1

Product Name Alternative

Cytochrome P450, CYP11B2 IN 1, CYP11B2IN1, CYP-11B2-IN-1, CYP11B2-IN-1

Field of Research

Metabolism Research

Purity

97.89% (May vary between batches)

Solubility

DMSO:50 mg/mL (160.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM)

Smiles

FC=1C=C2N (C (=NC2=CC1) C=3C=C (C (C) (C) O) C=NC3) C4CC4

Molecular Formula

C18H18FN3O

Molecular Weight

311.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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