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CYP17-IN-1

CYP17-IN-1 is a potent and orally bioavailable small molecule inhibitor of cytochrome P450 17A1 (CYP17) . It demonstrates strong inhibitory activity in both in vitro assays and in vivo models, with IC50 values of 15.8 nM in rats and 20.1 nM in humans. This compound is a valuable research tool for studying androgen biosynthesis in prostate cancer and related endocrine disorders.

Product Specifications

CAS Number

2093317-51-0

Product Name Alternative

Human CYP17, CYP17IN1, CYP-17-IN-1, CYP17-IN-1, CYP17 IN 1, CYP17, Rat CYP17

Field of Research

Metabolism Research

Purity

98.82% (May vary between batches)

Solubility

DMSO:3.13 mg/mL (10.02 mM)

Smiles

FC=1C=C2C3=C (SC2=CC1) CN (CC=4C (C) =CC=NC4) CC3

Molecular Formula

C18H17FN2S

Molecular Weight

312.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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