CYP17-IN-1
CYP17-IN-1 is a potent and orally bioavailable small molecule inhibitor of cytochrome P450 17A1 (CYP17) . It demonstrates strong inhibitory activity in both in vitro assays and in vivo models, with IC50 values of 15.8 nM in rats and 20.1 nM in humans. This compound is a valuable research tool for studying androgen biosynthesis in prostate cancer and related endocrine disorders.
Product Specifications
CAS Number
2093317-51-0
Product Name Alternative
Human CYP17, CYP17IN1, CYP-17-IN-1, CYP17-IN-1, CYP17 IN 1, CYP17, Rat CYP17
Field of Research
Metabolism Research
Purity
98.82% (May vary between batches)
Solubility
DMSO:3.13 mg/mL (10.02 mM)
Smiles
FC=1C=C2C3=C (SC2=CC1) CN (CC=4C (C) =CC=NC4) CC3
Molecular Formula
C18H17FN2S
Molecular Weight
312.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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