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DB1976

DB1976 is a potent, cell-permeable selenophene analog that acts as a fully efficacious PU.1 transcription factor inhibitor. It demonstrates high-affinity binding (KD ~12 nM) to disrupt PU.1/DNA complexes in vitro and induces apoptosis, supporting its research use in hematological studies and cancer research.

Product Specifications

CAS Number

1557397-51-9

Product Name Alternative

DB1976, DB-1976, DB 1976

Field of Research

Cell Biology

Purity

98.74% (May vary between batches)

Solubility

DMSO:50 mg/mL (111.77 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C (=N) (N) C=1C=C2NC (=NC2=CC1) C=3[Se]C (=CC3) C=4NC=5C (N4) =CC=C (C (=N) N) C5

Molecular Formula

C20H16N8Se

Molecular Weight

447.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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