DC0-NH2
DC0-NH2 is a highly potent DNA-alkylating agent, derived from the CBI moiety of DC1, with significantly enhanced stability. It exhibits superior cytotoxicity by binding the DNA minor groove and alkylating adenine residues, making it a model payload for ADC research and preclinical anticancer studies in vitro.
Product Specifications
CAS Number
615538-51-7
Smiles
Nc1ccc2[nH]c (cc2c1) C (=O) Nc1ccc2[nH]c (cc2c1) C (=O) N1C[C@@H] (CCl) c2c1cc (O) c1ccccc21
Molecular Formula
C31H24ClN5O3
Molecular Weight
550.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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