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DC1SMe

DC1 is a potent ADC cytotoxin that functions as a minor groove DNA alkylator, analogous to CC-1065. Its derivative, DC1Sme, exhibits sub-nanomolar cytotoxicity against various cancer cell lines, including Ramos and HL60 cells, making it a candidate for targeted cancer therapy research in both in vitro and in vivo models.

Product Specifications

CAS Number

501666-85-9

Smiles

C (Cl) [C@H]1C2=C (N (C (=O) C3=CC=4C (N3) =CC=C (NC (=O) C5=CC=6C (N5) =CC=C (NC (CCSSC) =O) C6) C4) C1) C=C (O) C=7C2=CC=CC7

Molecular Formula

C35H30ClN5O4S2

Molecular Weight

684.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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