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Midaglizole hydrochloride

Midaglizole hydrochloride (DG5128) is a selective α2-adrenoceptor antagonist with a 7.4-fold higher affinity for α2- versus α1-adrenoceptors (pKi = 6.28) . It is utilized in pharmacological research to study adrenergic signaling in both in vitro binding assays and in vivo models of cardiovascular and sympathetic nervous system function.

Product Specifications

CAS Number

79689-25-1

Product Name Alternative

DG5128 hydrochloride, DG-5128 Hydrochloride, DG 5128 Hydrochloride, (±) -DG5128 hydrochloride, Adrenergic Receptor, AdrenergicReceptor, Midaglizole Hydrochloride, α2-adrenoceptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.27% (May vary between batches)

Solubility

DMSO:45 mg/mL (138.78 mM)

Smiles

C1 (C (CC2=NCCN2) C3=CC=CC=C3) =NC=CC=C1.Cl.Cl

Molecular Formula

C16H19Cl2N3

Molecular Weight

324.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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