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DHODH-IN-14

DHODH-IN-14 is a hydroxyfuran pyrimidine analog and a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 of 0.49 μM against the mouse liver enzyme. This small molecule inhibitor is utilized in research areas such as immunology and rheumatology, particularly for investigating rheumatoid arthritis mechanisms in cellular and animal models.

Product Specifications

CAS Number

1364791-93-4

Product Name Alternative

DHODH, DHODH IN 14, DHODHIN14, DHODH-IN-14, Rat liver DHODH

Field of Research

Cell Biology, Metabolism Research, Molecular Biology

Purity

99.81% (May vary between batches)

Solubility

DMSO:50 mg/mL (141.55 mM)

Smiles

FC1=C (C (F) =C (F) C (NC (=O) C=2C (=O) NON2) =C1F) C3=CC=CC=C3

Molecular Formula

C15H7F4N3O3

Molecular Weight

353.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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