DHODH-IN-3
DHODH-IN-3 is a potent and selective inhibitor of human dihydroorotate dehydrogenase (HsDHODH), exhibiting an IC50 of 261 nM and binding with a Kiapp of 32 nM at the ubiquinone site. This compound shows promise as an antimalarial agent, supported by its activity in both enzymatic and cellular assays relevant to parasite proliferation.
Product Specifications
CAS Number
1148126-04-8
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Smiles
ClC=1C=C (C=CC1NC (/C (=C (/C) \O) /C#N) =O) C2=CC=CC=C2
Molecular Formula
C17H13ClN2O2
Molecular Weight
312.75
Storage Conditions
-20°C
Notes
For research use only.
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