DHODH-IN-4
DHODH-IN-4 is a dual inhibitor of Plasmodium falciparum and human dihydroorotate dehydrogenase (DHODH), with IC50 values of 4 μM and 0.18 μM, respectively. This compound demonstrates antimalarial activity and serves as a valuable chemical tool for studying pyrimidine biosynthesis in parasitology and enzymology research, both in vitro and in vivo.
Product Specifications
CAS Number
1148125-93-2
Product Name Alternative
DHODH IN 4, DHODH, DHODHIN4, DHODH-IN-4
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Purity
98.65% (May vary between batches)
Solubility
DMSO:55 mg/mL (158.41 mM)
Smiles
ClC1=C (C2=CC (Cl) =C (NC (/C (=C (/C) \O) /C#N) =O) C=C2) C=CC=C1
Molecular Formula
C17H12Cl2N2O2
Molecular Weight
347.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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