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DHODH-IN-4

DHODH-IN-4 is a dual inhibitor of Plasmodium falciparum and human dihydroorotate dehydrogenase (DHODH), with IC50 values of 4 μM and 0.18 μM, respectively. This compound demonstrates antimalarial activity and serves as a valuable chemical tool for studying pyrimidine biosynthesis in parasitology and enzymology research, both in vitro and in vivo.

Product Specifications

CAS Number

1148125-93-2

Product Name Alternative

DHODH IN 4, DHODH, DHODHIN4, DHODH-IN-4

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Purity

98.65% (May vary between batches)

Solubility

DMSO:55 mg/mL (158.41 mM)

Smiles

ClC1=C (C2=CC (Cl) =C (NC (/C (=C (/C) \O) /C#N) =O) C=C2) C=CC=C1

Molecular Formula

C17H12Cl2N2O2

Molecular Weight

347.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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