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Dihydroergocristine mesylate

Dihydroergocristine mesylate is a γ-secretase inhibitor that binds to Nicastrin, reducing amyloid-β peptide production. It has been researched in models of Alzheimer's disease and cerebrovascular insufficiency, and it functions as an alpha-adrenergic antagonist and vasodilator.

Product Specifications

CAS Number

24730-10-7

Product Name Alternative

Inhibit, Inhibitor, Abeta, bAmyloid, b Amyloid, Amyloid-β, amyloid-β, DHEC, DHEC (mesylate), Dihydroergocristine, Dihydroergocristine Mesylate, Dihydroergocristine mesylate, BetaAmyloid, Beta Amyloid, β Amyloid, β-amyloid peptide, βAmyloid

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.90% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.83 mM) ; DMSO:60 mg/mL (84.76 mM) ; H2O:1 mg/mL (1.41 mM)

Smiles

CS (O) (=O) =O.[H][C@@]12CCCN1C (=O) [C@H] (Cc1ccccc1) N1C (=O) [C@] (NC (=O) [C@H]3CN (C) [C@]4 ([H]) Cc5c[nH]c6cccc (c56) [C@@]4 ([H]) C3) (O[C@@]21O) C (C) C

Molecular Formula

C36H45N5O8S

Molecular Weight

707.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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