DYRKs-IN-1
DYRKs-IN-1 is a potent and selective small molecule inhibitor of DYRK1A and DYRK1B kinases, exhibiting IC50 values of 5 nM and 9 nM, respectively. It demonstrates antitumor properties and is a valuable chemical probe for studying DYRK family functions in cancer biology, cell cycle regulation, and neurodegenerative disease research in both cellular and animal models.
Product Specifications
CAS Number
1387090-01-8
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1N=C2NC (N3CC4OC (C3) CC4) =NC=C2C=C1C (NC5=CC (C (NC (CCN) C6=CC=CC=C6) =O) =CC=C5Cl) =O
Molecular Formula
C30H30ClN7O4
Molecular Weight
588.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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