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DYRKs-IN-1

DYRKs-IN-1 is a potent and selective small molecule inhibitor of DYRK1A and DYRK1B kinases, exhibiting IC50 values of 5 nM and 9 nM, respectively. It demonstrates antitumor properties and is a valuable chemical probe for studying DYRK family functions in cancer biology, cell cycle regulation, and neurodegenerative disease research in both cellular and animal models.

Product Specifications

CAS Number

1387090-01-8

Field of Research

Cell Biology, Signal Transduction

Smiles

O=C1N=C2NC (N3CC4OC (C3) CC4) =NC=C2C=C1C (NC5=CC (C (NC (CCN) C6=CC=CC=C6) =O) =CC=C5Cl) =O

Molecular Formula

C30H30ClN7O4

Molecular Weight

588.06

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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