Ecteinascidin 770

Ecteinascidin 770 is a small molecule that inhibits RNA-dependent RNA polymerase 1 (RDRP1), demonstrating antiviral activity against SARS-CoV-2 and antibacterial effects against Mycobacterium tuberculosis in vitro. Its primary research application is in oncology for studying cancer cell viability mechanisms.

Product Specifications

CAS Number

114899-80-8

Product Name Alternative

Ecteinascidin 770, Ecteinascidine 770, Et770, Et-770, U373MG cell

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Purity

99.84% (May vary between batches)

Solubility

DMSO:40 mg/mL (51.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.59 mM)

Smiles

C (#N) [C@@H]1N2[C@@] ([C@]3 (C=4C ([C@@]2 (COC (=O) [C@@]5 (CS3) C=6C (=CC (O) =C (OC) C6) CCN5) [H]) =C7C (=C (C) C4OC (C) =O) OCO7) [H]) ([C@]8 (C=9C (C[C@@]1 (N8C) [H]) =CC (C) =C (OC) C9O) [H]) [H]