Eg5 Inhibitor V, trans-24
Trans-24 is a potent and specific small molecule inhibitor of the mitotic kinesin Eg5, with an IC50 of 0.65 μM. It is a valuable chemical probe for studying cell division mechanisms and has been utilized in both in vitro biochemical assays and in vivo cancer research models to investigate antimitotic therapies.
Product Specifications
CAS Number
869304-55-2
Product Name Alternative
Eg5, Eg5 Inhibitor V, trans 24, Eg5 Inhibitor V, trans24, Eg-5 Inhibitor V, trans-24, Eg5 Inhibitor V, trans-24
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
97.45% (May vary between batches)
Solubility
DMSO:45 mg/mL (106.27 mM)
Smiles
[H][C@@]12Cc3c ([nH]c4ccccc34) [C@H] (N1C (=O) N (Cc1ccccc1) C2=O) c1cccc (O) c1
Molecular Formula
C26H21N3O3
Molecular Weight
423.46
Storage Conditions
-20°C
Notes
For research use only.
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