EGFR-IN-1 hydrochloride
EGFR-IN-1 hydrochloride is an irreversible, mutant-selective EGFR inhibitor targeting the L858R/T790M variants with high potency in cellular assays. It demonstrates significant antiproliferative effects in models like H1975 and HCC827 cells, supporting its utility in oncology research for studying resistance mechanisms and targeted therapy approaches.
Product Specifications
CAS Number
2227455-78-7
Product Name Alternative
EGFRL858R/T790M, EGFRIN1 hydrochloride, EGFR-IN-1 Hydrochloride, EGFR IN 1 hydrochloride, EGFR (L858R/T790M)
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.16% (May vary between batches)
Solubility
DMSO:10 mg/mL (18.15 mM)
Smiles
Cl.O=C (C=C) NC1=CC=CC (=C1) N2C (=O) C=C (C=3C=NC (=NC32) NC4=CC=C (OCCN (C) C) C=C4OC) C
Molecular Formula
C28H31ClN6O4
Molecular Weight
551.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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