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Elacestrant S enantiomer

The S enantiomer of Elacestrant is an orally bioavailable, selective estrogen receptor degrader (SERD) with preferential activity against ERα (IC50 = 48 nM) over ERβ (IC50 = 870 nM) . It is a research tool for investigating ER+ breast cancer mechanisms and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Product Specifications

Smiles

OC1=CC=C2C[C@@H] (C3=CC=C (OC) C=C3N (CC) CC4=CC=C (CCNCC) C=C4) CCC2=C1

Molecular Formula

C30H38N2O2

Molecular Weight

458.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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