FD 12-9

FD 12-9 is a flavonoid dimer compound demonstrating potent dual inhibition of the efflux transporters P-glycoprotein and BCRP, with EC50 values of 285 nM and 0.9 nM, respectively. Its ability to overcome multidrug resistance makes it a valuable research tool for investigating combination therapies in glioblastoma and other oncology models, both in vitro and in vivo.