FKBP12 PROTAC dTAG-13
DTAG-13 is a heterobifunctional PROTAC molecule designed for the selective degradation of FKBP12 (F36V) fusion proteins by recruiting the CRBN E3 ubiquitin ligase. It serves as a powerful chemical biology tool for target validation and studying protein function in both cellular and in vivo models, facilitating drug discovery research.
Product Specifications
CAS Number
2064175-41-1
Product Name Alternative
DTAG-13, BRD4, FKBP12 PROTAC dTAG 13, FKBP12 PROTAC dTAG13, FKBP-12 PROTAC dTAG-13, FKBP12 PROTAC dTAG-13, Epigenetic Reader Domain, EpigeneticReaderDomain
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.31% (May vary between batches)
Solubility
DMSO:80 mg/mL (76.25 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (3.15 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCCCCCCNC (COC4=C ([C@H] (OC (=O) [C@H]5N (C ([C@@H] (CC) C6=CC (OC) =C (OC) C (OC) =C6) =O) CCCC5) CCC7=CC (OC) =C (OC) C=C7) C=CC=C4) =O
Molecular Formula
C57H68N4O15
Molecular Weight
1049.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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